Angerer Pastillen, Anzeigenband zu Zeitschrift des allgemeinen österreichischen Apotheker-Vereines, June 20, 1894 A method of producing mercuric chloride by sublimation and desublimation from a mix of mercuric sulfate and salt was described by Johannes Kunckel (1630-1703) in his Laboratorio chemico, published in 1716. The mixture was heated in a sand bath and after it cooled, corrosive sublimate was found in the upper part of the vessel. In 1887, Ottmar von Angerer (1850-1918) designed a stable mixture of equal parts of sublimate and salt, to be dissolved in water. The Munich pharmacist Alfred Schillinger pressed it to make red pastilles dyed by eosin. In the 1920s, the Merck factory in Darmstadt produced small pastilles (after Schillinger) containing 0,5 and 1 g sublimate, for aseptic treatment of instruments, textiles and wounds, as well as larger pastilles after Friedrich von Esmarch (5 and 10 g) for disinfecting on a larger scale.